Talisman is a quest item found by Geralt during the quest Family Matters in The Witcher 3: Wild Hunt. Geralt finds the talisman by following the smell of wine from a broken bottle to one of the landings on the stairs where the talisman is hidden beneath a floor board.
"Freshly cut spruce sprinkled with goat's blood, then tempered with an incense of earthsmoke and juniper. For Anna. To protect her."