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For more information regarding Special ingredients, see Category:Special ingredients.
Substances Big Special

Special ingredients can be obtained by slaying unique monsters. These can be used to create unique potions called mutagens with powerful effects (often granting additional talents to be used to obtain skills, or granting special skills directly).

Item Special ingredient Potion Description
Substances Dagon secretions
Dagon secretions Dagon Sap Skinnable item obtained from Dagon.
Substances Frighteners claw
Frightener's claw Potion for Triss Skinnable item obtained from a frightener.
Substances Frighteners eye
Frightener's eye Frightener's Vision Skinnable item obtained from a frightener.
Substances Golems obsidian heart
Golem's obsidian heart Golem's Pith "Skinnable" item obtained from a golem, not that you could really skin a stone golem.
Substances Kikimore queens nerve
Kikimore queen's nerve Kikimore's Ire Skinnable item obtained from a kikimore queen.
Substances Koshchey heart
Koshchey heart Koshchey's Core Skinnable item obtained from a koshchey.
Substances Psilocybe
Psilocybe stronger fisstech Quest item for quest in Chapter III. Can not be used in alchemy.
Substances Skullhead talons
Skullhead talons unknown Skinnable item obtained from skullheads. Was not implemented in the game.
Substances Striga heart
Striga heart Striga's Urge Skinnable item obtained from the striga. You will not get this item if you decide not to kill Princess Adda.
Substances Trace of the beyond
Trace of the Beyond Hellhound's Soul Skinnable item obtained from the Beast.
Substances Vapors of the Hunt
Vapors of the Hunt unknown Skinnable item obtained from the King of the Wild Hunt.
Substances Werewolf fur
Werewolf fur Werewolf's Wrath Skinnable item obtained from a werewolf. You will not get this item if you decide not to kill Vincent Meis.
Substances Zeugl venom
Zeugl venom Zeugl's Vigor Skinnable item obtained from the zeugl.