- One can be found in St. Lebioda's Hospital, in the Temple Quarter.
- The other Shrine of Melitele is located in the Swamp.
The first sacrifice will give you three of the Sephirot: Ghe'vrath, 'Oth, Veen'ah. You will need these for the A Mysterious Tower and Monoliths tower quests. After this, every subsequent sacrifice will give you Mistletoe, an alchemical ingredient.