If talents are invested in more than one of these skills, the associated Adrenaline fueled abilities will be activated simultaneously.

The magic tree's Adrenaline Rush is provided by the Sense of Magic skill, which unleashes a sixth sign called the 'Heliotrope Sign' . This sign is activated by pressing the key when the Adrenaline bar is full. This sign slows down time in an area of effect, allowing Geralt to move and regenerate vigor faster relative to his enemies' speed.

The alchemy tree's Adrenaline Rush is provided by the Mutant skill, which unleashes a special buff called 'Battle Frenzy'. This buff is activated by pressing the key when the Adrenaline bar is full. This buff augments Geralt, allowing him to regenerate vitality faster and pull off heavier hits with his main melee attacks.

The swordsmanship tree's Adrenaline Rush is provided by the Combat acumen skill, which unleashes a special ability called 'Group Finishers'. This ability is activated by pressing the key when the Adrenaline bar is full. This ability gives Geralt the ability to kill the nearest three enemies, in a 'group finisher' move, which is only possible if they all have relatively low health.